Oral Administration of Brain Protein Combined With Probiotics

Oral Administration of Mind Protein Mixed With Probiotics Induces Immune Tolerance By the Tryptophan Pathway

Extreme irritation results in secondary immune injury after traumatic mind damage (TBI). The intestinal mucosa is a key part of immune tolerance as a result of gut-brain axis regulation, however the healing impact just isn’t optimum. Intestinal dysfunction impairs the institution of immune tolerance in sufferers with TBI. Subsequently, we orally administered mind protein (BP) mixed with probiotics to induce immune tolerance and explored the mechanism by which the homeostasis of the microbiota contributes to the enhancement of healing results by BPs. Herein, we demonstrated that sufferers with TBI and surgical mind damage (SBI) fashions of rats had apparent dysbiosis. Notably, the intestinal barrier, proinflammatory cytokines, and activation of microglia demonstrated that extreme inflammatory injury was higher managed within the mixed group (oral administration of BP mixed with probiotics) than within the BP group (oral administration of BP). Essentially, tandem mass tag (TMT)-based quantitative proteomics evaluation revealed that BP and probiotics preferentially have an effect on Strive-related pathways.

A collection of experiments additional confirmed that Indoleamine 2,three dioxygenase (IDO)/Kynurenine (Kyn)/Aryl hydrocarbon receptor (AhR) expression was excessive within the BP group, whereas Tryptophan hydroxylase 1(TpH1)/5-hydroxytryptamine (5-HT) solely modified within the mixed group. This examine means that probiotics can improve the efficacy of oral BP-induced immune tolerance via the Strive pathway.

C reactive protein to albumin ratio (CAR) as predictor of anastomotic leakage in colorectal surgical procedure

Background: Anastomotic leakage (AL) is likely one of the most extreme problems in colorectal surgical procedure. Presently, no predictive biomarkers of AL can be found. The goal of this examine was to research the position of C reactive protein (CRP) to albumin ratio (CAR) as a predictor of AL in sufferers present process elective surgical procedure for colorectal most cancers.

Supplies and strategies: Knowledge on 1183 consecutive sufferers surgically handled for histologically confirmed colorectal most cancers within the surgical models concerned within the examine had been collected. Knowledge included intercourse, age, BMI, ASA rating, Charlson comorbidity index, localization, histology and stage of the illness, in addition to blood assessments together with albumin and CRP at the 4th postoperative day. Variations in CAR between sufferers who developed AL and those that didn’t had been analyzed, and the flexibility of CAR to foretell AL was investigated with ROC evaluation.

Outcomes: CAR was considerably larger in sufferers with AL compared to these with out, on the 4th postoperative day. In ROC evaluation CAR confirmed a superb capability in detecting AL (AUC 0.825, 95%CI: 0,786-0,859), higher than these of CRP and albumin alone. CAR additionally confirmed a excessive capability in detecting postoperative deaths (AUC 0.750, 95% CI 0,956-0,987). These findings had been confirmed in multivariate evaluation together with probably the most related threat components for AL.

Conclusion: Our examine evidenced that CAR, a cheap and extensively obtainable laboratory biomarker, adequately predicts AL and demise in sufferers who underwent elective surgical procedure for colorectal most cancers.

yeastevolution
yeastevolution

Anti-CD207 antibody (Alexa-fluor 488)

STJ170014 100 µg
EUR 393
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307)

Anti-IL7R antibody (Alexa-fluor 488)

STJ170020 100 µg
EUR 393
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54)

Anti-RPSA Alexa Fluor® 488

A4-829-C100 0.1 mg
EUR 310

Goat anti Mouse IgG1 (Alexa Fluor 488)

43R-1649 500 ug
EUR 570
Description: Goat anti Mouse IgG1 secondary antibody (Alexa Fluor 488)

Anti-Hu CD16 Alexa Fluor® 488

A4-646-T100 100 tests
EUR 269

Nuclear Pore Complex antibody

10R-8370 100 ul
EUR 349
Description: Mouse monoclonal Nuclear Pore Complex antibody

Anti-Nuclear pore Complex antibody

STJ120173 100 µl
EUR 469

AF488 Phalloidin [equivalent to Alexa Fluor® 488 phalloidin]

23153 300 Tests
EUR 306
  • R-phrase: R23, R24, R25
  • H-Phrase: H301, H311, H331
  • Symbol for dangerous compounds: T
  • UNSPEC Code: 12352200

AF488-streptavidin conjugate [Streptavidin, Alexa Fluor™ 488 Conjugate]

16891 1 mg
EUR 176
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12171501

Anti-Hu CD72 Alexa Fluor® 488

A4-310-T100 100 tests
EUR 269

Anti-Bov CD9 Alexa Fluor® 488

A4-354-C100 0.1 mg
EUR 269

Endoglin/CD105 Alexa Fluor

FC15024 100 Tests
EUR 448

Goat Anti-Mouse IgG(H+L) Alexa Fluor 488–conjugated

S0017 200ul
EUR 304

Goat Anti-Rabbit IgG(H+L) Alexa Fluor 488–conjugated

S0018 200ul
EUR 304

Nuclear pore complex protein Nup153 Antibody

20-abx109340
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Panspecific Nuclear Pore Complex Marker

MO22107 500 ul
EUR 344

Anti-LAMP3 (human) Monoclonal Antibody (104G4) (Alexa Fluor® 488)

M09406 100ug
EUR 565
Description: Mouse Monoclonal LAMP3 (human) Antibody (104G4) (Alexa Fluor® 488). Validated in IHC and tested in Human.

Donkey Anti-Rabbit IgG (H+L), Alexa Fluor® 488 Conjugated

Ab8032-001 0.5mg
EUR 435

Anti-Hu CD3 zeta (pY153) Alexa Fluor® 488

A4-686-C100 0.1 mg
EUR 269

Anti-Hu CD3 zeta (pY72) Alexa Fluor® 488

A4-712-C100 0.1 mg
EUR 269

Anti-Hu CD3 zeta (pY142) Alexa Fluor® 488

A4-730-C100 0.1 mg
EUR 269

Anti-Hu CD3 zeta (pY111) Alexa Fluor® 488

A4-737-C100 0.1 mg
EUR 269

Anti-LAMP3 antibody (Alexa-fluor 546)

STJ170005 100 µg
EUR 393
Description: The dendritic cell lysosomal-associated membrane protein (DC-LAMP)/CD208 is a type I integral transmembrane glycoprotein mostly homologous to CD68, of about 45 kDa in mouse and 90 kDa in human (glycosylation), with a bipartite C-terminal structure divided by a serine/proline rich region, a transmembrane domain and a conserved tyrosine-based lysosomal targeting motif in its cytoplasmic tail. Initially cloned as a specific marker of human mature dendritic cells (DCs), DC-LAMP has been subsequently shown to be expressed in alveolar type II pneumocytes. In both cell types, the molecule is found in the limiting membrane of intracellular multi-lamellar bodies, known as MIIC (MHC class II compartments) in human mature DCs and as lung surfactant-containing lamellar bodies in type II pneumocytes. In the latter cell type, DC-LAMP expression is also detected at the cell surface.

Anti-LAMP3 antibody (Alexa-fluor 647)

STJ170006 100 µg
EUR 393
Description: The dendritic cell lysosomal-associated membrane protein (DC-LAMP)/CD208 is a type I integral transmembrane glycoprotein mostly homologous to CD68, of about 45 kDa in mouse and 90 kDa in human (glycosylation), with a bipartite C-terminal structure divided by a serine/proline rich region, a transmembrane domain and a conserved tyrosine-based lysosomal targeting motif in its cytoplasmic tail. Initially cloned as a specific marker of human mature dendritic cells (DCs), DC-LAMP has been subsequently shown to be expressed in alveolar type II pneumocytes. In both cell types, the molecule is found in the limiting membrane of intracellular multi-lamellar bodies, known as MIIC (MHC class II compartments) in human mature DCs and as lung surfactant-containing lamellar bodies in type II pneumocytes. In the latter cell type, DC-LAMP expression is also detected at the cell surface.

Anti-IL3RA antibody (Alexa-fluor 546)

STJ170010 100 µg
EUR 393
Description: IL3 exerts its biologic activity through its interaction with a cell surface receptor that consists of two subunits. The a subunit (CD123) specifically binds IL3, whereas the ß subunit is required for signaling and is common to the GMCSFR and IL5-R. 107D2.08 and 106C2.02 mAbs were obtained after mouse immunization with sorted human tonsillar PDC. Both clones strongly stain PDCs and basophils, weakly stain monocytes, CD34+ derived DCs and CD11c+ DC, while no staining is observed on T, B, NK cells as well as on mono-derived DCs. Staining with 107D2.08 and 106C2.02 mAbs are maintained on sorted PDC cultured in the presence of IL3 and CD40L, but lost when IL3 alone is added to the culture. The recognition of the IL3Ra chain by 107D2.08 and 106C2.02 was confirmed by transfection studies. 107D2.08 appeared to be the most appropriate clone for in situ studies. 107D2.08 allowed the first observation of IL3Ra+ cells in breast tumor microenvironment

Anti-IL3RA antibody (Alexa-fluor 647)

STJ170011 100 µg
EUR 393
Description: IL3 exerts its biologic activity through its interaction with a cell surface receptor that consists of two subunits. The a subunit (CD123) specifically binds IL3, whereas the ß subunit is required for signaling and is common to the GMCSFR and IL5-R. 107D2.08 and 106C2.02 mAbs were obtained after mouse immunization with sorted human tonsillar PDC. Both clones strongly stain PDCs and basophils, weakly stain monocytes, CD34+ derived DCs and CD11c+ DC, while no staining is observed on T, B, NK cells as well as on mono-derived DCs. Staining with 107D2.08 and 106C2.02 mAbs are maintained on sorted PDC cultured in the presence of IL3 and CD40L, but lost when IL3 alone is added to the culture. The recognition of the IL3Ra chain by 107D2.08 and 106C2.02 was confirmed by transfection studies. 107D2.08 appeared to be the most appropriate clone for in situ studies. 107D2.08 allowed the first observation of IL3Ra+ cells in breast tumor microenvironment

Anti-CD207 antibody (Alexa-fluor 546)

STJ170015 100 µg
EUR 393
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307)

Anti-CD207 antibody (Alexa-fluor 647)

STJ170016 100 µg
EUR 393
Description: Langerin/CD207 is a transmembrane C-type lectin receptor (CLR) of epidermal and mucosal Langerhans cells (LCs) that induces Birbeck's granule formation. Langerin features a single carbohydrate recognition domain (CRD) with mannose-type specificity in its extracellular portion. Langerin is unique among the CLRs in that it contains an intracellular domain with a proline-rich motif. Langerin expression has not been reported outside the DC system. (Valladeau J et al, 1999, Eur.J.Immunol., 29:2695-2704; Valladeau J et al, 2000 Immunity, 12 : 71-81; Kashihara M et al, 1986, J.Invest.Derm., 87 :602-607 Ito T et al, 1999, J.Immunol., 163 :1409-1419 ;Saeland S & Valladeau J, CD207 (Langerin) Workshop reports 2002, Leukocyte-Typing VII, White Cell Diff Antigens, D. Mason et al, Eds, Oxford University Press:306-307)

Anti-IL7R antibody (Alexa-fluor 546)

STJ170021 100 µg
EUR 393
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54)

Anti-IL7R antibody (Alexa-fluor 647)

STJ170022 100 µg
EUR 393
Description: The IL7-R consists of 2 chains, IL-7R known as CD127 and common cytokine receptor chain known as CD132. A 75 to 80kDa human IL-7 receptor has been cloned that belongs to hematopoietic cytokinereceptor super family. R34-34, raised against human leukemic pre-B cells, recognized a molecule expressed on normal B cell precursors but not on mature B cells. This antibody specifically reverted IL-7 mediated growth inhibition of leukemic BCP (normal B cells precursors) and mature T cells. IL-7R expression is dramatically influenced by cytokines and antigens. This IL-7R displays both high and low affinity for its ligand (IL-7). Inhibitory and proliferative effects of IL-7 can be mediated through the same receptor on various lineages. CD4+ memory T cells express high level of IL-7R Subsets that express it generally require it, including progenitors of T and B cells, naïve and memory T cells. (Pandrau-Garcia D et al, 1994, Blood, 83, 3613-9 Mazzucchelli R et al, Nat. Review Immunol., 2007,7, 144-54)

SAM FCM (Alexa Fluor 647)

abx098902-100tests 100 tests
EUR 1233
  • Shipped within 5-10 working days.

Nuclear pore complex protein Nup153 Antibody (Biotin)

20-abx105728
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Nuclear pore complex protein Nup153 Antibody (FITC)

20-abx107146
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Nuclear pore complex protein Nup153 Antibody (HRP)

20-abx108567
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Anti-Langerin (human) Monoclonal Antibody (DCGM4/122D5) (Alexa Fluor® 488)

M02316 100ug
EUR 580
Description: Mouse Monoclonal Langerin (human) Antibody (DCGM4/122D5) (Alexa Fluor® 488). Validated in IHC and tested in Human.

Alpha Fluor™ 488 amine

1705 1 mg
EUR 306
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12171501

Alpha Fluor™ 488 Hydroxylamine

1900 1 mg
EUR 306
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12171501

Human Nuclear pore complex protein Nup153 (NUP153)

1-CSB-EP016190HU
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 27.3 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Human Nuclear pore complex protein Nup153(NUP153),partial expressed in E.coli

Nuclear pore complex protein Nup98 (315-360)

HY-P1730 1mg
EUR 1140

Recombinant human Nuclear pore complex protein Nup133

P2220 100ug Ask for price
  • Uniprot ID: Q8WUM0
  • Reconstitution: Metal affinity chromatography on Fn Super Capacity Column (Nickel)
Description: Recombinant protein for human Nuclear pore complex protein Nup133

Nuclear Pore Complex-Interacting Protein-Like 2 (NPIPL2) Antibody

abx034938-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

Nuclear Pore Complex-Interacting Protein-Like 2 (NPIPL2) Antibody

abx034938-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

Alpha Fluor™ 488 NHS Ester

1812 1 mg
EUR 219
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12171501

Streptavidin-Alexa488 (Alexas fluor 488) conjugate

SV-A488-100 100 tests
EUR 225

Rabbit Anti-Rat IgG (H+L)-Alexa 488 Fluor conjugate (adsorbed with human IgG)

50336 0.5 ml
EUR 225

Alpha Fluor™ 532 acid [equivalent to Alexa Fluor™ 532 acid]

1795 10 mg
EUR 393
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12171501

Human Nuclear pore complex protein Nup155, NUP155 ELISA KIT

ELI-15040h 96 Tests
EUR 824

Mouse Nuclear pore complex protein Nup50, Nup50 ELISA KIT

ELI-15055m 96 Tests
EUR 865

Human Nuclear pore complex- interacting protein, NPIP ELISA KIT

ELI-16689h 96 Tests
EUR 824

Mouse Nuclear pore complex protein Nup54, Nup54 ELISA KIT

ELI-21319m 96 Tests
EUR 865

Mouse Nuclear pore complex protein Nup160, Nup160 ELISA KIT

ELI-21357m 96 Tests
EUR 865

Mouse Nuclear pore complex protein Nup214, Nup214 ELISA KIT

ELI-21358m 96 Tests
EUR 865

Human Nuclear pore complex protein Nup50, NUP50 ELISA KIT

ELI-22432h 96 Tests
EUR 824

Bovine Nuclear pore complex protein Nup85, NUP85 ELISA KIT

ELI-23491b 96 Tests
EUR 928

Mouse Nuclear pore complex protein Nup85, Nup85 ELISA KIT

ELI-23492m 96 Tests
EUR 865

Mouse Nuclear pore complex protein Nup155, Nup155 ELISA KIT

ELI-44221m 96 Tests
EUR 865

Human Nuclear pore complex protein Nup214, NUP214 ELISA KIT

ELI-44222h 96 Tests
EUR 824

Bovine Nuclear pore complex protein Nup93, NUP93 ELISA KIT

ELI-44229b 96 Tests
EUR 928

Mouse Nuclear pore complex protein Nup133, Nup133 ELISA KIT

ELI-44499m 96 Tests
EUR 865

Mouse Nuclear pore complex protein Nup93, Nup93 ELISA KIT

ELI-44561m 96 Tests
EUR 865

Human Nuclear pore complex protein Nup153, NUP153 ELISA KIT

ELI-44867h 96 Tests
EUR 824

Human Nuclear pore complex protein Nup133, NUP133 ELISA KIT

ELI-46087h 96 Tests
EUR 824

Mouse Nuclear pore complex protein Nup88, Nup88 ELISA KIT

ELI-35536m 96 Tests
EUR 865

Mouse Nuclear pore complex protein Nup107, Nup107 ELISA KIT

ELI-38239m 96 Tests
EUR 865

Human Nuclear pore complex protein Nup160, NUP160 ELISA KIT

ELI-38240h 96 Tests
EUR 824

Human Nuclear pore complex protein Nup205, NUP205 ELISA KIT

ELI-38242h 96 Tests
EUR 824

Human Nuclear pore complex protein Nup85, NUP85 ELISA KIT

ELI-36779h 96 Tests
EUR 824

Human Nuclear pore complex protein Nup88, NUP88 ELISA KIT

ELI-36780h 96 Tests
EUR 824

Human Nuclear pore complex protein Nup93, NUP93 ELISA KIT

ELI-36781h 96 Tests
EUR 824

Human Nuclear pore complex protein Nup107, NUP107 ELISA KIT

ELI-36840h 96 Tests
EUR 824

SEC13 Homolog, Nuclear Pore And COPII Coat Complex Component (SEC13) Antibody

abx025879-400ul 400 ul
EUR 523
  • Shipped within 5-10 working days.

SEC13 Homolog, Nuclear Pore And COPII Coat Complex Component (SEC13) Antibody

abx025879-80l 80 µl
EUR 286
  • Shipped within 5-10 working days.

SEC13 Homolog, Nuclear Pore And COPII Coat Complex Component (SEC13) Antibody

20-abx123660
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul
  • Shipped within 5-10 working days.

SEC13 Homolog, Nuclear Pore And COPII Coat Complex Component (SEC13) Antibody

20-abx126518
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

SEC13 Homolog, Nuclear Pore And COPII Coat Complex Component (SEC13) Antibody

abx237677-100ug 100 ug
EUR 509
  • Shipped within 5-12 working days.

Mouse IgG1-Alexa 488 conjugate (isotype control)

20102-101-A488 50 Tests
EUR 263

Human Nuclear pore complex protein Nup98- Nup96, NUP98 ELISA KIT

ELI-13775h 96 Tests
EUR 824

ELISA kit for Rat Nuclear pore complex protein Nup153 (NUP153)

KTE100879-48T 48T
EUR 332
  • Nuclear pore complexes are extremely elaborate structures that mediate the regulated movement of macromolecules between the nucleus and cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to th
  • Show more
Description: Quantitative sandwich ELISA for measuring Rat Nuclear pore complex protein Nup153 (NUP153) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Nuclear pore complex protein Nup153 (NUP153)

KTE100879-5platesof96wells 5 plates of 96 wells
EUR 2115
  • Nuclear pore complexes are extremely elaborate structures that mediate the regulated movement of macromolecules between the nucleus and cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to th
  • Show more
Description: Quantitative sandwich ELISA for measuring Rat Nuclear pore complex protein Nup153 (NUP153) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Rat Nuclear pore complex protein Nup153 (NUP153)

KTE100879-96T 96T
EUR 539
  • Nuclear pore complexes are extremely elaborate structures that mediate the regulated movement of macromolecules between the nucleus and cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to th
  • Show more
Description: Quantitative sandwich ELISA for measuring Rat Nuclear pore complex protein Nup153 (NUP153) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

AF350 Phalloidin [equivalent to Alexa Fluor® 350 phalloidin]

23150 300 Tests
EUR 306
  • R-phrase: R23, R24, R25
  • H-Phrase: H301, H311, H331
  • Symbol for dangerous compounds: T
  • UNSPEC Code: 12352200

AF594 Phalloidin [equivalent to Alexa Fluor® 594 phalloidin]

23158 300 Tests
EUR 306
  • R-phrase: R23, R24, R25
  • H-Phrase: H301, H311, H331
  • Symbol for dangerous compounds: T
  • UNSPEC Code: 12352200

AF350-streptavidin conjugate [Streptavidin, Alexa Fluor™ 350 Conjugate]

16890 1 mg
EUR 176
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12171501

AF594-streptavidin conjugate [Streptavidin, Alexa Fluor™ 594 Conjugate]

16892 1 mg
EUR 176
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12171501

Donkey anti Goat IgG (H + L) (Alexa Fluor 594)

43R-ID005AF 500 ug
EUR 338
Description: Donkey anti Goat IgG (H + L) secondary antibody (Alexa Fluor 594)

Donkey anti Rat IgG (H + L) (Alexa Fluor 594)

43R-ID022AF 500 ug
EUR 364
Description: Donkey anti Rat IgG (H + L) secondary antibody (Alexa Fluor 594)

Donkey anti Goat IgG (H + L) (Alexa Fluor 647)

43R-ID028AF 500 ug
EUR 430
Description: Donkey anti Goat IgG (H + L) secondary antibody (Alexa Fluor 647)

Donkey anti Rat IgG (H + L) (Alexa Fluor 594)

43R-ID047AF 500 ug
EUR 462
Description: Donkey anti Rat IgG (H + L) secondary antibody (Alexa Fluor 594)

Donkey anti Chicken IgY (H + L) (Alexa Fluor 594)

43R-ID056AF 500 ug
EUR 343
Description: Donkey anti Chicken IgY secondary antibody (H + L) (Alexa Fluor 594)

Donkey anti Chicken IgY (H + L) (Alexa Fluor 647)

43R-ID060AF 300 ug
EUR 425
Description: Donkey anti Chicken IgY (H + L) (Fab'2) (Alexa Fluor 647)

Rabbit anti Chicken IgY (H + L) (Alexa Fluor 594)

43R-IR016AF 1 mg
EUR 281
Description: Rabbit anti Chicken IgY (H + L) secondary antibody (Alexa Fluor 594)

Anti-Hu CD30 Alexa Fluor® 700

A7-455-T100 100 tests
EUR 269

Anti-Hu CD94 Alexa Fluor® 700

A7-727-T100 100 tests
EUR 269

Anti-Hu CD56 Alexa Fluor® 700

A7-789-T100 100 tests
EUR 269

Nuclear pore membrane glycoprotein 210 Antibody

20-abx110055
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Recombinant Human Nuclear pore complex protein Nup153 Protein, His, E.coli-100ug

QP6439-ec-100ug 100ug
EUR 408

Recombinant Human Nuclear pore complex protein Nup153 Protein, His, E.coli-10ug

QP6439-ec-10ug 10ug
EUR 200

Recombinant Human Nuclear pore complex protein Nup153 Protein, His, E.coli-1mg

QP6439-ec-1mg 1mg
EUR 1632

Recombinant Human Nuclear pore complex protein Nup153 Protein, His, E.coli-200ug

QP6439-ec-200ug 200ug
EUR 634

Recombinant Human Nuclear pore complex protein Nup153 Protein, His, E.coli-500ug

QP6439-ec-500ug 500ug
EUR 1060

Recombinant Human Nuclear pore complex protein Nup153 Protein, His, E.coli-50ug

QP6439-ec-50ug 50ug
EUR 263

Goat Anti-Mouse IgG(H+L) Alexa Fluor 594–conjugated

S0005 200ul
EUR 376

Goat Anti-Rabbit IgG(H+L) Alexa Fluor 594–conjugated

S0006 200ul
EUR 376

Goat Anti-Rabbit IgG(H+L) Alexa Fluor 647–conjugated

S0013 200ul
EUR 304

Goat Anti-Mouse IgG(H+L) Alexa Fluor 647–conjugated

S0014 200ul
EUR 304

Nuclear pore membrane glycoprotein 210 Polyclonal Antibody

42276-100ul 100ul
EUR 333

Nuclear pore membrane glycoprotein 210 Antibody (Biotin)

20-abx105729
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Nuclear pore membrane glycoprotein 210 Antibody (FITC)

20-abx107147
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Nuclear pore membrane glycoprotein 210 Antibody (HRP)

20-abx108568
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Nuclear Pore Associated Protein 1 (NPAP1) Antibody

20-abx339916
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Nuclear Pore Associated Protein 1 (NPAP1) Antibody

20-abx339917
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Mouse pre-microRNA Expression Construct mir-488

MMIR-488-PA-1 Bacterial Streak
EUR 684
  • Category: MicroRNA Tools

Donkey anti Goat IgG (H + L) (Fab 2) (Alexa Fluor 594)

43R-ID012AF 300 ug
EUR 410
Description: Donkey anti Goat IgG (H + L) secondary antibody (Fab'2) (Alexa Fluor 594)

Donkey Anti-Goat IgG (H+L), Alexa Fluor® 594 Conjugated

Ab8011-001 1mg
EUR 334

Anti-Hu CD3 zeta (pY153) Alexa Fluor® 647

A6-686-C100 0.1 mg
EUR 269

Anti-Hu CD3 zeta (pY72) Alexa Fluor® 647

A6-712-C100 0.1 mg
EUR 269

Anti-Hu CD3 zeta (pY142) Alexa Fluor® 647

A6-730-C100 0.1 mg
EUR 269

Anti-Hu CD3 zeta (pY111) Alexa Fluor® 647

A6-737-C100 0.1 mg
EUR 269

Recombinant rat Nuclear pore glycoprotein p62

P1858 100ug Ask for price
  • Uniprot ID: P17955
  • Reconstitution: Metal affinity chromatography on Fn Super Capacity Column (Nickel)
Description: Recombinant protein for rat Nuclear pore glycoprotein p62

Nuclear Pore Membrane Glycoprotein 210-Like (NUP210L) Antibody

20-abx217285
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Nuclear Pore Membrane Glycoprotein 210-Like (NUP210L) Antibody

20-abx121185
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Nuclear pore membrane glycoprotein 210 Polyclonal Conjugated Antibody

C42276 100ul
EUR 397

Human SEC13 Homolog, Nuclear Pore And COPII Coat Complex Component (SEC13) ELISA Kit

abx383083-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.

Proliferating Cell Nuclear Antigen (PCNA) Antibody (ATTO 488)

abx445975-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Human Nuclear pore membrane glycoprotein 210 (NUP210)

1-CSB-EP016195HU(C)
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 34.5 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Human Nuclear pore membrane glycoprotein 210(NUP210),partial expressed in E.coli

Human Nuclear pore membrane glycoprotein 210 (NUP210)

1-CSB-EP016195HU(N)
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 27.6 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Human Nuclear pore membrane glycoprotein 210(NUP210),partial expressed in E.coli

Rabbit anti-Nuclear pore glycoprotein p62 antiserum

NUP6211-S 100 ul
EUR 457

Nuclear Pore-Associated Protein 60 kDa-Like (Npap60) Antibody

abx430652-200ul 200 ul
EUR 384
  • Shipped within 1-3 working days.

Microtubule-Associated Proteins 1A/1B Light Chain 3A (MAP1LC3A) Antibody (ATTO 488)

abx447726-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

Human Nuclear pore glycoprotein p62, NUP62 ELISA KIT

ELI-22574h 96 Tests
EUR 824

Mouse Nuclear pore glycoprotein p62, Nup62 ELISA KIT

ELI-38235m 96 Tests
EUR 865

Rabbit Anti-Rat IgG (H+L)-Alexa 594 Fluor conjugate (adsorbed with human IgG)

50337 0.5 ml
EUR 225

Lys proteins Antibody

DF2705 200ul
EUR 304
Description: Lys proteins antibody detects endogenous levels of total Lys proteins.

Lys proteins Antibody

abx219526-100ug 100 ug
EUR 439
  • Shipped within 5-10 working days.

Lys proteins Antibody

ABD2705 100 ug
EUR 438

Human Nuclear pore membrane glycoprotein 210, NUP210 ELISA KIT

ELI-19703h 96 Tests
EUR 824

Mouse Nuclear pore membrane glycoprotein 210, Nup210 ELISA KIT

ELI-45547m 96 Tests
EUR 865

Control/Blocking Peptide Nuclear pore membrane glycoprotein Nup210 (GP210)

GP210-11C 100 ug
EUR 225

Rabbit anti-Nuclear pore membrane glycoprotein Nup210 (GP210) antiserum

GP210-11S 100 ul
EUR 457

Nuclear Factor Erythroid 2-Related Factor 2 (NRF2) Antibody (ATTO 488)

abx445941-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

T-Complex Protein 1 Subunit Alpha (TCP1 alpha) Antibody (ATTO 488)

abx440517-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

T-Complex Protein 1 Subunit Alpha (TCP1 alpha) Antibody (ATTO 488)

abx440518-100ug 100 ug
EUR 551
  • Shipped within 5-12 working days.

Nuclear Factor of Activated T-Cells, Cytoplasmic 1 (NFATC1) Antibody (ATTO 488)

abx445924-100ug 100 ug
EUR 578
  • Shipped within 5-12 working days.

The position of TRIM proteins in PRR signaling pathways and immune-related ailments

Sample recognition receptors (PRRs) are a type of recognition molecules primarily expressed on innate immune cells. PRRs acknowledge a number of sorts of pathogen-associated molecular patterns (PAMPs), inducing the manufacturing of interleukin (IL), tumor necrosis issue (TNF), interferon (IFN) and different associated cytokines to worsen immune-related ailments. PPR signaling pathways play an essential position in each innate and adaptive immune system, and they’re simple to be activated or regulated.

Tripartite motif (TRIM) proteins are a bunch of extremely conserved proteins in construction. Most of TRIM proteins comprise RING area, which is believed to play a job in ubiquitination. TRIM proteins are concerned in viral immunity, inflammatory response, autophagy, and tumor development. On this evaluation, we concentrate on the regulation of TRIM proteins on PRR signaling pathways and their roles in immune-related ailments.

A fluorescent molecular imaging probe with selectivity for soluble tau aggregated protein

Soluble types of aggregated tau misfolded protein, typically termed oligomers, are thought-about to be probably the most poisonous species of the completely different meeting states which are the pathological parts of neurodegenerative issues. Subsequently, a vital biomedical want exists for imaging probes that may establish and quantify them. We’ve designed and synthesized a novel fluorescent probe, pTP-TFE for which binding and selectivity profiles in direction of aggregated tau and Aβ proteins had been assessed. Our outcomes have proven pTP-TFE to be selective for early types of soluble tau aggregates, with excessive affinity of dissociation constants (Ok d) = 66 nM, and tenfold selectivity over mature tau fibrils.

Moreover, we discovered that pTP-TFE is selective for tau over Aβ aggregates and had good cell permeability. This selectivity of pTP-TFE in direction of early types of aggregated tau protein ex vivo was additionally supported with research on human mind tissue containing tau and Aβ pathology. To the very best of our data, that is the primary fluorescent molecule to be reported to have this type of selectivity profile, which means that pTP-TFE is a singular probe candidate for imaging-based detection of early phases of Alzheimer’s illness and different tauopathies.

Reconstituted cryopreserved platelets synthesize proteins throughout short-term storage and packaging an outlined subset into microvesicles

Background: Cryopreservation of platelets (PLTs) may enable extension of their shelf-life to years, in comparison with days for liquid saved platelets. As a result of their higher hemostatic impact, reconstituted cryopreserved platelets (cryo-PLTs) would have the ability to help bleeding emergencies. Since protein synthesis has been linked to PLT capabilities, reminiscent of clot formation and immune responses, the translational capability of reconstituted cryo-PLTs was assessed upon thawing and short-term storage.

Strategies/supplies: Platelets had been frozen at -80°C with 5-6% DMSO. Upon thawing, they had been reconstituted in plasma after which aliquoted (12 ml) into mini-bags and assessed over 24 h of storage at RT. One collection served as management; the second and third collection had been spiked with both 300 μM puromycin (Pm) or 227 nM biotin-labeled Pm. Samples had been examined for in vitro high quality and PLT microvesicle enumeration by circulate cytometry. Protein synthesis in cryo-PLTs was assessed utilizing a modified technique based mostly on puromycin-associated nascent chain proteomics.

Outcomes: In vitro parameters of reconstituted and subsequently saved platelets had been in keeping with beforehand printed outcomes. Mass-spectrometry analyses recognized that 22 proteins had been synthesized in PLTs and 13 of these had been noticed in platelet microvesicles (PMVs).

Conclusion: Cryo-PLTs can synthesize proteins upon reconstitution and storage. Discovery of a subset of those proteins within the PMV suggests a job in vesicle encapsulation, probably in a selective method. This remark offers novel insights into the capability for protein synthesis in cryo-PLTs and the potential regulation of protein packaging into PMV.

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